GitHub上排名靠前的Python开源项目：

1.
httpie
 
(git)

Command line HTTP client, human-friendly cURL replacement.

2.
django
 
(git) ：

The Web framework for perfectionists with deadlines.(http://pythonhackers.com/open-source/django/django)

3.
requests
 
(git)

Python HTTP Requests for Humans™.

4.
flask
 
(git)

A microframework based on Werkzeug, Jinja2 and good intentions

5.
ansible
 
(git)

Ansible is a radically simple IT orchestration engine that makes your applications and systems easier to deploy. Avoid writing scripts or custom code to deploy and update your applications— automate in a language that approaches plain English, using SSH, with no agents to install on remote systems.

6.
tornado
 
(git)

Tornado is a Python web framework and asynchronous networking library, originally developed at FriendFeed.

7.
reddit
 
(git)

the code that powers reddit.com

8.
the-swift-programming-language-in-chinese
 
(git)

中文版 Apple 官方 Swift 教程《The Swift Programming Language》

9.
awesome-python
 
(git)

A curated list of awesome Python frameworks, libraries and software. Inspired by awesome-php.

10.
Probabilistic-Programming-and-Bayesian-Methods-for-Hackers
 
(git)

aka “Bayesian Methods for Hackers”: An introduction to Bayesian methods + probabilistic programming with a computation/understanding-first, mathematics-second point of view. All in pure Python ;)